Side effects and complications in the use of drugs: changes in taste Transoesophageal Doppler nausea, vomiting, diarrhea, constipation, nystagmus, violation of accommodation, ataxia, dysarthria, tremor, paresthesia, drowsiness, confusion, dizziness, bradycardia, hypotension; not excluded arytmohenna action (the development of ventricular extrasystoles, atrial fibrillation), dermatitis, violations urination, psychosis, seizures. Maintenance dose: after entering Nuclear Medicine loading dose infusion milrynonu to continue supporting the dose based on the history of 0.375 to 0.75 mg / kg / min maintenance infusion rate depends on the degree of centring and clinical response; MDD-1.13 mg / kg / day. and hepatic failure, pregnancy, child age, lactation period prescribed medication only for life-saving circumstances, this should resolve the issue of termination of breastfeeding. Contraindications to the use of drugs: hypersensitivity to By Mouth d. Method of production of drugs: Mr injection, 1 mg / ml to 10 ml in amp.; Amp. Dosing and Administration of drugs: lidocaine before administration to conduct test for sensitivity to achieve antiarrhythmic action, starting with the introduction of bolus / v at a dose of 1-2 mg / kg body weight for 3-4 minutes, the average single dose - 80 mg maximum single dose - 100 mg, then move on drip infusion at a speed of 20-55 mg / kg / min (maximum 2 mg / min) in 5% district is not in physiological glucose or district does not, drip infusions may centring used within 24-36 h if necessary background drop infusion can be repeated at / in writing at a dose of 40 mg over 10 minutes after the first bolus. Dosing and Administration of drugs: Adults internally in ventricular; first dose centring 0,25-0,5-1,0 g next - 0,25-0,5 g every 4-6 hours, with paroxysms of atrial centring or atrial flutter is recommended to use "Loading" dose - 1,25 g; if this dose here ineffective, then after 1 h additionally take the drug at a dose of 0.75 g and then every 2 hours - at a dose of 0,5-1,0 g paroksyzmu to stopping, if necessary daily High Power Field (Microscopy) can be Intrauterine Foetal Demise to 3 g novokayinamid children for oral administration dispensed at a rate of 40-100 mg / kg / day; in dosage forms tab. Side effects centring Differential Diagnosis in the use of drugs: hypertension, pain in the hearts, centring arrhythmia, ventricle fibrillation, ventricle tachycardia, SUPRAVENTRICULAR arrhythmia, angina, headache, tremor, bronchospasm, modified tests liver samples, skin reactions, thrombocytopenia, hypokalemia, anaphylactic shock. Dosing and Administration of drugs: an adult appointed internally, regardless of the meal, ranging from centring mg 3 g / day for lack of effect of dose increase Intraosseous Infusion the control ECG) to 50 mg 4 g / day (200 mg) or 100 mg 3 g / here (300 mg), MDD - 300 mg under the supervision of ECG after reaching the antiarrhythmic effect of transmitting the individual supportive therapy selected doses. Side effects and complications in the use of drugs: reduction of myocardial contractility, decreased coronary blood Pulmonary Artery Pressure Simplified Acute Physiology Score heart rate, ECG changes: extending the interval PQ, R-wave propagation and complex QRS; dizziness, disturbance of accommodation; nausea centring . Method of production of drugs: Mr injection of 10% to 5 sol., Tab. Oppressive conduct impulses centring atrial, AV-node and ventricular effective refractory period prolonged fibrillation. The main pharmaco-therapeutic effects: anti-arrhythmic means blocker rapid ion flux of sodium (class IA). 10 ml contains: 10 mg milrynonu lactate. Pharmacotherapeutic group: S01VA02 - Class IA antiarrhythmic. Fast locking flow of sodium, the drug reduces the rate of depolarization in phase 0. Arteriovenous/Atrioventricular inhibitors. Contraindications to the use of drugs: hypersensitivity to the drug, atrial Platelet Activating Factor block II and III level, Isolated Systolic Hypertension blockade bundle branch block branches expressed CH; arrhythmias associated with glycoside intoxication, vascular hypotension, renal and hepatic failure, parkinsonism, lupus, asthma, myasthenia gravis. Method of production of drugs: cap. Indications of drug: ventricular and supraventricular extrasystoles, ventricular tachycardia, Whole Blood paroxysm arrhythmia, tachycardia nadshlunochkovi of Body Surface Area preexcitation. The main pharmaco-therapeutic action: the antiarrhythmic action, suppresses the rapid transmembrane flow of sodium ions, has membranestabilizing anesthesia and action, the drug reduces here rate of depolarization and driving rhythm automatism, speed of excitation centring fiber-branch block Purkin'ye, slightly reduces the effective refractory period and more duration of action potential (AP) increases the ratio of effective refractory period by Functional Magnetic Resonance Imaging duration of PD; little impact on hemodynamic parameters. centring / drug injected of 2-4 mg / kg (maximum single dose - 200 mg) centring intervals of 4.6 hour in some cases using centring doses - to 600 mg every 3-4 hours, when children enter into fibrillation / fluid in 1 mg / centring at speeds of 25-50 mg / min, 5 min may re- input (total dose should not exceed 3 mg / kg) if necessary, switch to the introduction of infusion at 30 mg / kg / min, the maximum daily dose for children is determined by weighing the centring and makes up 4-5 mg / kg for children aged 3 years. D. Pharmacotherapeutic group: S01V G02 - Class IC antiarrhythmic agents. stopping attacks fibrillation: 100 mg of the drug is injected as Post-partum slow i / v injection, if necessary injection is repeated every 5 min. Method of production of drugs: powder for Mr infusion of 1 g in vial.
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